首页 > 研究队伍 > 刘宏伟课题组 > 代表性文章专著及专利

2016年】

1.         Qiaoqiao Tao#, Ke Ma#, Li Bao, Kai Wang, Junjie Han, Wenzhao Wang, Jinxia Zhang, Chenyang Huang, Hongwei Liu*. Sesquiterpenoids with PTP1B Inhibitory Activity and Cytotoxicity from the Edible Mushroom Pleurotus citrinopileatus. Planta Medica, 2016, 82, 639-644. (IF = 2.319)

2.         Qiaoqiao Tao#, Ke Ma#, Li Bao, Kai Wang, Junjie Han, Jinxia Zhang, Chenyang Huang,Hongwei Liu*. New sesquiterpenoids from the edible mushroom Pleurotus cystidiosus and their inhibitory activity against α-glucosidase and PTP1B. Fitoterapia. 2016, 111, 29-35. (IF = 2.631)

3.         Qiaoqiao Tao#, Ke Ma#, Yanlong Yang, Kai Wang, Baosong Chen, Ying Huang, Junjie Han, Li Bao, Xiao-Bin Liu, Zhuliang Yang, Wen-Bing Yin, Hongwei Liu*. Bioactive Sesquiterpenes from the Edible Mushroom Flammulina velutipes and Their Biosynthetic Pathway Confirmed by Genome Analysis and Chemical Evidence. Journal of Organic Chemistry. 2016, 81, 9867-9877 (IF = 4.538)

4.         Jin Tian#, Junjie Han#, Xue Zhang*, Luwei He, Yongjie Zhang, Li Bao, Hongwei Liu*. New Cyclohexadepsipeptides from an Entomogenous Fungus Fusarium proliferatum and Their Cytotoxicity and Autophagy-inducing Activity. Chemistry & Biodiversity, 2016, 13, 852-860. (IF=1.735)

5.         Song Wang, Xiaoqin Luo, Ruoxiang Yan, Quanxin Wang, Qiuyue Qi, Xiaojuan Chi, Lanlan Zhang, Ziding Yu, Binxiang Cai, Ji-Long Chen*, Hongwei Liu*. 3-anhydro-6-hydroxy-ophiobolin A displays high in vitro and in vivo efficacy against influenza A virus infection. Protein & Cell. 2016, 7, 839-843.(IF=3.043)

6.         Luwei He#, Junjie Han#, Baowei Li, Li Huang, Ke Ma, Quan Chen, Xinzhong Liu, Li Bao,Hongwei Liu*. Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity. European Journal of Medicinal Chemistry. 2016, 111, 183-192. (IF=3.982)

7.         Kai Wang#, Li Bao#, Ke Ma, Wei Qi, Fuhang Song, Yijian Yao, Wenbing Yin, Lixin Zhang, Ying Huang, Junjie Han, Hongwei Liu*. Bioactive Spirobisnaphthalenes and Lactones from a Cup Fungus Plectania sp. Collected in the Tibet Plateau Region. European Journal of Organic Chemistry. 2016, 4338-4346. (IF=2.971)

8.         Kai Wang#, Li Bao#, Ke Ma, Jinjin Zhang, Baosong Chen, Junjie Han, Jinwei Ren, Hongwei Liu*. A novel class of α- glucosidase and HMG-CoA reductase inhibitors from Ganoderma leucocontextum and the anti-diabetic properties of ganomycin I in KK-Ay mice. European Journal of Medicinal Chemistry. doi:10.1016/j.ejmech.2016.11.015 (IF=3.982)

9.         Jin Xin, Junjie Han, Shuxian Yang, Yuan Hu, Hongwei Liu *, Feng Zhao *. 11-O-acetylcyathatriol inhibits MAPK/p38-mediated inflammation in LPS-activated RAW 264.7 macrophages and has a protective effect on ethanol-induced gastric injury, Molecular medicine reports. 2016, 14, 874-880. (IF=1.617)



2015年】

 1.   Li Huang#, Junjie Han#, Danya Ben-Hail, Luwei He, Baowei Li, Ziheng Chen, Yueying Wang, Yanlei Yang, Lei Liu, Yushan Zhu, Varda Shoshan-Barmatz*, Hongwei Liu*, Quan Chen*. A new fungal diterpene induces VDAC1-dependent apoptosis in Bax/Bak-deficient cells. The Journal of Biological Chemistry. 2015, 290, 23563-78

2.        Kai Wang#, Li Bao#, Weiping Xiong#, Ke Ma, Junjie Han, Wenzhao Wang, Wenbing Yin,Hongwei Liu*. Lanostane triterpenes from the Tibetan Medicinal Mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and a-glucosidase. Journal of Natural Products. 2015, 78, 1977-1989.

3.       Kangji Wang, Zhenying Zhang, Xi Chen, Xianyun Sun, Cheng Jin, Hongwei Liu*, Shaojie Li*. Transcription factor ADS-4 regulates adaptive responses and resistance to antifungal azole stress. Antimicrob Agents Chemother. 2015, 59, 5396-5404.

4.       Qiuyue Qi#, Jinwei Ren#, Liwei Sun, Luwei He, Li Bao, Wei Yue, Qinmiao Sun, Yijian Yao, Wenbing Yin, Hongwei Liu*. Stucturally Diverse Sesquiterpenes Produced by a Chinese Tibet Fungus Stereum hirsutum and their Cytotoxic and Immunosuppressant ActivitiesOrganic Letters. 2015, 17 (12), 3098-3101.

5.       Qiuyue Qi#, Erwei Li#, Junjie Han, Yunfei Pei, Ke Ma, Li Bao*, Ying Huang, Feng Zhao, Hongwei Liu*. New ambuic acid derivatives from the solid culture of Pestalotiopsis neglecta and their nitric oxide inhibitory activity. Scientific Reports. 2015, 5, 9958.

6.       Junjie Han#, Li Bao#, Qiaoqiao Tao, Yijian Yao, Xingzhong Liu, Wenbing Yin,Hongwei Liu*. Gloeophyllins A-J, cytotoxic ergosteroids with various skeletons from a Chinese Tibet fungus Gloeophyllum abietinum. Organic Letters. 2015, 17, 2538-2541.

7.       Kai Wang, Li Bao, Qiuyue Qi, Feng Zhao, Ke Ma, Yunfei Pei, Hongwei Liu*. Erinacerins C-L, Isoindolini-1-ones with a-glucosidase inhibitory activity form cultures of the medicinal mushroom Hericium erinaceusJournal of Natural Products. 2015, 78:146-154.

8.       Ke Ma, Li Li, Li Bao, Luwei He, Chen Sun, Bing Zhou, Shuyi Si, Hongwei Liu*. Six new 3,4-seco-27-norlanostane triterpenes from the medicinal mushroom Ganoderma boninense and their antiplasmodial activity and agonistic activity to LXRβ. Tetrahedron. 2015, 71, 1808-1814.

9.      Danfeng Xue, Quanxin Wang, Ziheng Chen, Lei Cai, Li Bao, Qiuyue Qi, Lei Liu, Xiaohui Wang, Haijing Jin, Jun Wang, Hao Wu*, Hongwei Liu*, Quan Chen*. 3-Anhydro-6-hydroxy-ophiobolin A, a fungal sesterterpene from Bipolaris oryzae induced autophagy and promoted the degradation of α-synuclein in PC12 cells. Bioorganic Medicinal Chemistry Letters. 2015, 25, 1464-1470

10.     Junjie Han, Lei Zhang, Jiekun Xu, Li Bao, Feng Zhao, Yuhui Chen, Weiku Zhang*,Hongwei Liu*. Three new cyathane diterpenoids from the medicinal fungus Cyathus africanus.Journal of Asian Natural Products Research. 2015, 17, 541-549.

11.     Kai Wang#, Li Bao#, Ke Ma, Ning Liu, Ying Huang, Jinwei Ren, Wenzhao Wang, Hongwei Liu*. Eight new alkaloids with PTP1B and a-glucosidase inhibitory activity from the medicinal mushroom Hericium erinaceusTetrahedron. 2015, 1, 9557-9563.

 

2014年】

 

1.        Qiuyue Qi#, Li Bao#, Jinwei Ren, Junjie Han, Zongyao Zhang, Yi Li, Yijian Yao, Rui Cao, Hongwei Liu*. Sterhirsutins A and B, Two New Heterodimeric sesquiterpenes with a new skeleton from the culture of Stereum hirsutum collected in Tibet Plateau.Organic Letters, 2014, 16, 5092-5095.

2.        Ke Ma#, Junjie Han#, Li Bao, Tiezheng Wei, Hongwei Liu*. Two sarcoviolins with antioxidative and α-Glucosidase inhibitory activity from the edible mushroomSarcodon leucopus collected in Tibet. Journal of Natural Products, 2014, 77, 942-947.

3.        Ke Ma, Li Bao, Junjie Han, Tao Jin, Xiaoli Yang, Feng Zhao,Shaifei Li, Fuhang Song, Miaomiao Liu, and Hongwei Liu*. New benzoate derivatives and hirsutane type sesquiterpenoids with antimicrobial activity and cytotoxicity from the solid-state fermented rice by the medicinal mushroom Stereum hirsutumFood Chemistry, 2014, 143, 239-245. 

4.        Ke Ma#, Jinwei Ren#, Junjie Han, Li Bao, Li Li, Yijian Yao, Chen Sun, Bing Zhou, Hongwei Liu*. Ganoboninketals A−C, antiplasmodial 3,4-seco-27-norlanostane triterpenes from Ganoderma boninense Pat. Journal of Natural Products, 2014, 77, 1847-1852.

5.        Botao Wang#, Junjie Han#, Wei Xu*, Yuhui Chen, Hongwei Liu*. Production of bioactive cyathane diterpenes by a bird’s nest fungus Cyathus gansuensis growing on cooked rice. Food Chemistry, 2014, 152, 169-176.

6.        Botao Wang#, Qiuyue Qi#, Ke Ma, Yunfei Pei, Junjie Han, Wei Xu, Erwei Li,Hongwei Liu*. Depside α-Glucosidase inhibitiors from a culture of the mushroom Stereum hirsutum. Planta Medica, 2014, 80: 918-924.

7.        Shimei Wang#, Junjie Han#, Ke Ma, Tao Jin*, Li Bao, Yunfei Pei, Hongwei Liu*. New α-Glucosidase inhibitors with p-terphenyl skeleton from the mushroom Hydnellum concrescensFitoterapia, 2014, 98: 149-155.

8.       Feng Zhao, Yuan Hu, Chuanke Chong, Minghui Lu, Liping Chen, Weijuan Kan, Lei Chen, Hongwei Liu*. Ardisiphenol D, a resorcinol derivative identified from Ardisia brevicaulis, exerts antitumor effect through inducing apoptosis in human non-small-cell lung cancer A549 cells. Pharmaceutical Biology, 2014, 52, 797-803.

9.       Qiuyue Qi, Li Huang, Luwei He, Junjie Han, Quan Chen, Lei Cai, Hongwei Liu. Cochlioquinone Derivatives with Apoptosis-Inducing Effects on HCT116 Colon Cancer Cells from the Phytopathogenic Fungus Bipolaris luttrellii L439. Chemistry & Biodiversity.2014, 11, 1892-1899.



专著

Traditional Herbal Medicine Research Methods: Identification, Analysis, Bioassay, and Pharmaceutical and Clinical Studies. John Wiley & Sons, Inc, 2010(第3章)

 


授权专利

 

1.  刘宏伟,张小青,宝丽。一株中华隐孔菌及其固体培养方法与应用。授权专利号:ZL201010135110.0

2.  刘宏伟,韩俊杰,陈玉惠,宝丽. 11-氧乙酰鸟巢烷三醇和15-氧乙酰鸟巢烷三醇的生产方法及其专用菌株。授权专利号:ZL20121 0352773.7.

3.  刘宏伟,宝丽,王雅琪。来源于金针菇的倍半萜化合物的新用途。授权专利号:ZL201110051193.X.

4.  刘宏伟,宝丽,王雅琪。一种降倍半萜类化合物及其制备方法与应用。授权专利号:ZL201110443960.1

5.  刘宏伟,张立新,王全新,郭良栋。蛇孢菌素类二倍半萜化合物及其制备方法与应用。授权专利号:ZL201110431751.5 

6.  刘宏伟,王全新,宝丽,韩俊杰。Coicenal类二萜化合物及其制备方法和在制备抗炎药物中的应用。授权专利号:ZL 201310254586.X 

7.  刘宏伟,韩俊杰,宝丽. 一种鸟巢烷类二萜化合物在制备抗肿瘤药物中的应用。授权专利号:ZL 201210352484.7

8.  刘宏伟,宝丽. 一种杏鲍菇功能性食品及其制备方法。授权专利号:ZL 201210380590.6

9.  刘宏伟,马轲,韩俊杰,宝丽. 两种三联苯并二恶嗪衍生物及其应用. 授权专利号:ZL 201410056590.x. 

10.  刘宏伟,王全新,宝丽,陈吉龙。一种化合物、该化合物的制备方法以及化合物在制备抗肿瘤药物中的应用。授权专利号:ZL 201310093409.8

11.  刘宏伟,韩俊杰,赵烽,宝丽. 11-氧乙酰鸟巢烷三醇在制备预防和/或治疗胃溃疡药物中的应用,授权专利号:ZL 201410376678.X. 

12.  刘宏伟,韩俊杰. 二萜类化合物及其基于抗肿瘤的应用,授权专利号:ZL 201310556420.3.

13.  刘宏伟,王波涛,马轲,齐秋月,韩俊杰. 苯甲酸衍生物及其制备与降糖应用. 授权专利号:ZL 201410111365.1. 

14.  刘宏伟,马轲,韩俊杰,宝丽. 一种Sarcodon leucopus中降糖活性成分及其制备方法与应用. 授权专利号:ZL 201410056448.5.

15.  刘宏伟,汪锴,宝丽,韩俊杰. 异吲哚类化合物及其应用. 授权专利号:ZL 201410394697.5