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代表性文章、专著、专利等成果清单

 

[1] Jin, C. (2011) Protein glycosylation in Aspergillus fumigatus is essential for cell wall synthesis and serves as a promising model of multi-cellular eukaryotic development. Int. J. Microbiol., Volume 2012, Article ID 654251 (doi:10.1155/2012/654251).[特邀综述]

[2] 金城(2011)丝状真菌糖生物学. 生命科学, 23(6):541-554.[特邀综述]

[3] Song, L., Zhou, H., Cai, X., Li, C., Liang, J., and Jin, C. (2011) NeuA O-acetylesterase is essential for capsular sialic acid synthesis and traversal of blood-brain barrier in E. coli and Streptococcus suis serotype 2. Biochem. Biophys. Res. Commun., 410: 212-217.

[4] Li, K., Ouyang, H., Lü, Y., Liang, J., Wilson, I. B. H., and Jin, C. (2011) Repression of N-glycosylation triggers the unfolded protein response (UPR) and over-expression of cell wall protein and chitin in Aspergillus fumigatus. Microbiol., 157: 1968-1979.

[5] Fang, W., Ding, W., Wang, B., Zhou, H., Ouyang, H., Ming, J., and Jin, C. (2010) Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus. Glycobiology, 20(5):542-552.

[6] Ouyang, H., Luo, Y., Zhang, L., Li, Y., and Jin, C. (2010) Proteome analysis of Aspergillus fumigatus total membrane proteins identifies proteins associated with the glycoconjugates and cell wall biosynthesis using 2D LC-MS/MS. Mol. Biotechnol., 44:177-189.

[7] Fang, W., Yu, X., Wang, B., Zhou, H., Ouyang, H., Ming, J., and Jin, C. (2009) Characterization of the Aspergillus fumigatus phosphomannose isomerase Pmi1 and its impact on cell wall synthesis and morphogenesis. Microbiol., 155: 3281-3293.

[8] Lü, Y., Yang, H., Hu, H., Wang, Y., Rao, Z., and Jin, C. (2009) Mutation of Trp137 to glutamate completely removes transglycosyl activity associated with the Aspergillus fumigatus AfChiB1. Glycoconjugate J., 26:525-534.

[9] Zhang, L., Feng, D., Fang, W., Ouyang, H., Luo, Y., Du, T., and Jin, C. (2009) Comparative proteomic analysis of an Aspergillus fumigatus mutant deficient in glucosidase I (AfCwh41). Microbiol., 155: 2157-2167.

[10] Li, Y., Fang, W., Zhang, L., Ouyang, H., Zhou, H., Luo, Y., and Jin, C. (2009) Class IIC α-mannosidase AfAms1 is required for morphogenesis and cellular function in Aspergillus fumigatus. Glycobiol., 19 (6): 624-632.

[11] 陈晓敏, 欧阳浩淼, 唐国敏, 王敖全, 金城 (2008) 烟曲霉蛋白质分泌载体的构建及酸性磷酸酯酶的细胞定位. 微生物学报, 48: 1330-1338.

[12] Zhang, L., Zhou, H., Ouyang, H., Li, Y., and Jin, C. (2008) Afcwh41 is required for cell wall synthesis, conidiation, and polarity in Aspergillus fumigatus. FEMS Microbiol. Lett., 289(2):155-166.

[13] Jiang, H., Ouyang, H., Zhou, H., and Jin, C. (2008) GDP-mannose pyrophosphorylase is essential for cell wall integrity, morphogenesis and viability of Aspergillus fumigatus. Microbiol., 154:2730-2739.

[14] Li, Y., Zhang, L., Wang, D., Zhou, H., Ouyang, H., Ming, J., and Jin, C. (2008) Deletion of the msdS gene induces abnormal polarity and septation in Aspergillus fumigatus. Microbiol., 154:1960-1972.

[15] Zhuo, H., Hu, H., Zhang, L., Li, R., Ouyang, H., Ming, J., and Jin, C. (2007) Protein O-mannosyltransferase 1 (AfPmt1p) in Aspergillus fumigatus is crucial for cell wall integrity and conidia morphology especially at an elevated temperature. Eukaryotic Cell, 6(12):2260-2268.

[16] Li, H., Zhou, H., Luo, Y., Ouyang, H., Hu, H., and Jin, C. (2007) Glycosylphosphatidylinositol (GPI)-anchor is required in Aspergillus fumigatus for morphogenesis and virulence. Mol. Microbiol., 64(4):1014-1027.

[17] Wang, D. P., Li, H. G., Li, Y. J., Guo, S. C., Yang, J., Qi, D. L., Jin, C., and Zhao, X. Q. (2006) Hypoxia-inducible factor 1alpha cDNA cloning and its mRNA and protein tissue specific expression in domestic yak (Bos grunniens) from Qinghai-Tibetan plateau. Biochem. Biophys. Res. Commun., 348(1):310-319.

[18] 王颖, 王俊琦, 胡红焱, 杨雪鹏, 杨寿钧, 余小应, 金城 (2004) 烟曲霉几丁质酶基因的克隆与表达. 生物工程学报, 20(6):843-850.

[19] Liu, G., Jin, C., and Jin, C. (2004) CMP-N-acetylneuraminic acid synthetase from E. coli K1 is a bi-functional enzyme: Identification of minimal catalytic domain for synthetase activity and novel functional domain for platelet-activating factor acetylhydrolase activity. J. Biol. Chem., 279(17): 17738-17749.

[20] Hu, H., Wang, G., Yang, H., Zhou, J., Mo, L., Yang, K., Jin, C., Jin, C., and Rao, Z. (2004) Crystallization and preliminary crystallographic analysis of a native chitinase from the fungal pathogen Aspergillus fumigatus YJ-407. Acta Crystallogr. D Biol. Crystallogr., 60(Pt 5):939-940.

[21] Gu, G., Du, Y., Hu, H., and Jin, C. (2003) Synthesis of 2-chloro-4-nitrophenyl a-L-fucopyranoside: a substrate for a-L-fucosidase (AFU). Carbohydrate Research, 338:1603-1607.

[22] Xia, G., Jin, C., Zhou, J., Yang, S., Zhang, S., and Jin, C. (2001) A novel chitinase having a unique mode of action from Aspergillus fumigatus YJ-407. Eur. J. Biochem., 268(14):4079-4085.

[23] Liu, J., Zhou, R., Zhang,N., Rui, J., and Jin, C. (2000) Biological function of a novel gene overexpressed in human hepatocellular carcinoma. Chinese Medical Journal, 113(10):881-885.

[24] Xia, G., Han, X., Ding, H., Yang, S., Zhang, S., and Jin, C.(2000)Cloning and overexpression of a cytidine 5’-monophosphate N-acetylneuraminic acid synthetase from Escherichia coli. J. Molecular Catalysis B: Enzymatic, 10:201-208.

[25] Liu, N., Jin, C., Zhu, Z., Tao, H., and Zhang S.(1999)Stage-specific expression of 1,2-fucosyltransferase and 1,3-fucosyltransferase (FT) during mouse embryogenesis. Eur. J. Biochem., 265: 258-263.

[26] Shang, J., Qiu, R., Wang, J., Liu, J., Zhou, R., Yang, S., Zhang S., and Jin, C.(1999)Molecular cloning and expression of Gal1,3GalNAc 2,3-sialyltransferase from human fetal liver. Eur:J.Biochem., 265:580-588.

 

参加会议及报告

[1] 金城.微生物糖链代谢酶的研究. 第四届全国酶工程学术交流讨论会, 大会报告, 2003年10月12-17日, 无锡.

[2] Jin, C. Glycosylation in Aspergillus fumigatus. The 8th China-Japan-Korea Joint Symposium on Enzyme Engineering, Keynote Lecture, Oct.24-26, 2004, Hangzhou, China.

[3] 金城. 微生物的糖基化与功能. 资源生物技术与糖工程学术研讨会, 大会报告, 2005年7月7-9日, 济南, 中国.

[4] 金城. 微生物糖组学研究. 中国生物工程学会年会, 大会报告, 2005年7月16-18日, 天津, 中国.

[5] Jin, C. Glycosylation pathway in Aspergillus fumigatus. Enzyme Engineering XVIII, invited speaker, Oct.9-14, 2005, Gyeong-ju, Korea.

[6] 金城. 烟曲霉糖蛋白的糖基化及功能. 第五届中国酶工程学术研讨会, 大会报告, 2005年 11月15-20日, 海口, 中国.

[7] 金城. 丝状真菌甘露糖基化生物合成途径及其生物学功能. 第一届全国糖生物学会议, 大会报告, 2006年8月20-22日, 大连, 中国.

[8] Yang, X., Yang S., Han B., and Jin C. Structure and function of β-Glycosidase from Thermus nonproteolyticus. The 9th Japan-China-Korea Joint Symposium on Enzyme Engineering, Oral presentation, Oct.30-Nov.2, 2006, Otsu, Japan.

[9] 金城. 烟曲霉(Aspergillus fumigatus) 几丁质酶Chi44的结构与功能. 中国甲壳素及其衍生物专家研讨会, 大会报告, 2007年6月2-3日, 青岛, 中国.

[10] 金城. 丝状真菌蛋白质糖基化及其生物学功能. 第二届资源生物技术与糖工程学术研讨会, 大会报告, 2007年7月14-17日, 威海, 中国.

[11] 金城. 丝状真菌甘露糖基化生物合成途径及其生物学功能. 2007年微生物学会学术年会, 大会报告, 2007年8月12-16日, 乌鲁木齐, 中国.

[12] Jin, C. Mutation of Trp137 to glutamate completely removes transglycosyl activity associated with the Aspergillus fumigatus AfChiB1. The 10th Korea-China-Japan Joint Symposium on Enzyme Engineering, Nov. 2-5, 2008, Bushan, Korea.

[13] Jin, C. Glycosidase and glycosyltransferase in fungus Aspergillus fumigatus. Commemorative Symposium on Enzyme Engineering --- the 30th Anniversary of Japanese Society of Enzyme Engineering, Invited lecture, Nov. 13-15, 2008, Kisaradu, Japan.

[14] Jin, C. Glycosidase and glycosyltransferase in fungus Aspergillus fumigatus. ISHAM 2009 Beijing Satellite Symposia,Invited lecture, May 29-31, 2009, Beijing, China.

[15] Jin, C. Glycosylation is required for cell wall biogenesis and morphogenesis in opportunistic fungus Aspergillus fumigatus. The 1st Asian Conference of Glycobiology and Glycotechnology, Invited lecture, Oct. 28-Nov.1, 2009, Tsukuba, Japan.

[16] Jin, C. Functional analysis of glycosylation in filamentous fungus Aspergillus fumigatus. 第七屆海峽兩岸真菌學學術研討會, Nov.13-22, 2009, 台湾。

[17] Jin, C. Bi-functional NeuA protein from Streptocossus suis. 2009 Sino-German Symposium on Streptococcus Infectious Diseases and Beyond, Invited lecture, Dec. 2-3, 2009, Guangzhou, China.

[18] 金城. 烟曲霉的发病机制——毒力因子与抗真菌药物靶点. 首届曲霉与曲霉病新进展高峰论坛. 特邀报告,2010年7月16-18日,成都.

[19] 金城. 真菌糖生物学——揭示糖链复杂功能的突破口?2010年全国糖生物学学术会议, 大会报告, 2010年8月10-13日,长春.

[20] 金城. 蛋白质糖基化修饰的功能研究. 2010年北京生物化学与分子生物学会年会, 大会报告, 2010年12月4日,北京.

[21] Jin, C. Glycosylation and its function in the filamentous fungus Aspergillus fumigatus. Invited lecture in Department of Chemistry, University of Natural Resources and Life Sciences, Feb.14, 2011, Vienna, Austria.

[22] Jin, C. Synthesis and regulation of capsular sialic acid in E. coli and Streptococcus suis serotype 2. The third Asian Conference of Glycobiology and Glycotechnology, Invited lecture, Oct. 27-29, 2011, Shanghai, China.

[23] Jin, C. Glycosylation and its function in Aspergillus fumigatus. 2011 Annual Conference of the Society for Glycobiology, invited lecture, Nov.12, 2011, Seattle, USA.